Oncoscience


2024 Press Releases

Targeting Carbohydrate Metabolism in Colorectal Cancer: Synergy of Therapies



2024-11-15

“This commentary will discuss what is known about such combinatorial treatments, including potential mechanisms and future protocols.”



BUFFALO, NY - November 15, 2024 – A new review was published in Oncoscience (Volume 11) on November 12, 2024, entitled, “Targeting carbohydrate metabolism in colorectal cancer - synergy between DNA-damaging agents, cannabinoids, and intermittent serum starvation.”

As highlighted by the authors in the abstract of this review, chemotherapy is a common

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Tribute to Dr. Mikhail (Misha) Blagosklonny



2024-10-22

It is with great sadness and heavy heart that we announce the recent passing of Dr. Mikhail (Misha) V. Blagosklonny, our beloved Editor-in-Chief. Misha succumbed to metastatic lung cancer after a courageous battle.

Dr. Blagosklonny will be remembered as a brilliant and extraordinary scientist who dedicated his life to science. He was a visionary thinker, who made highly original contributions to cancer and aging research that were often ahead of their time.

Dr. Blagosklonny was born into a

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Long-lasting Immunotherapy Response in Stage IV Lung Cancer with Brain Metastasis



2024-10-18

“In the last decade, immunotherapy agents changed the treatment landscape for Non-Small Cell Lung Cancer (NSCLC).”



BUFFALO, NY - October 18, 2024 – A new case report was published in Oncoscience (Volume 11) on October 8, 2024, entitled, “Complete and long-lasting response to immunotherapy in a stage IV non-small cell lung cancer with brain metastasis.”

As highlighted in the abstract of this report, approximately 20% of lung cancer patients have brain metastases at diagnosis, which is

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Challenge of Weight Gain in Hormone Receptor-Positive Breast Cancer



2024-09-27

“This study highlighted patterns of weight gain among early-stage HR+ breast cancer, especially among those with healthy BMI or overweight after cancer diagnosis.”

BUFFALO, NY - September 27, 2024 – A new editorial was published in Oncoscience (Volume 11) on September 23, 2024, entitled, “The challenge of weight gain in hormone receptor-positive breast cancer.”

As introduced in this editorial, obesity is associated with an increased risk of developing... continue reading >>

Functional Information Offers Individualized Adaptive Cancer Therapies



2024-08-30

“Functional information is an emerging research area that needs participation from all fields of precision medicine.”

BUFFALO, NY - August 30, 2024 – A new editorial was published in Oncoscience (Volume 11) on July 19, 2024, entitled, “Functional information offers individualized adaptive cancer therapies.”

As introduced in this editorial, the Oxford Computer Science Dictionary offers both general and technical definitions of information. Generally,... continue reading >>

Retrotransposon DNA Zip Code for Myeloma Cell Internalization



2024-08-09

“GT is a fascinating evolutionary phenomenon observed in lower species and humans, albeit with differing impacts and mechanisms.”



BUFFALO, NY - August 09, 2024 – A new editorial was published in Oncoscience (Volume 11) on July 13, 2024, entitled, “Unveiling retrotransposon-derived DNA zip code for myeloma cell internalization.”

The complex interplay between extracellular genetic material and the tumor's genetic landscape presents a significant challenge in grasping cancer evolution,

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Targeting Factors for Chemoprevention and Cancer Interception to Tackle Mesothelioma



2024-07-19

“In this research perspective, we review the current state of chemoprevention and cancer interception progress in asbestos-induced mesothelioma.”



BUFFALO, NY - July 19, 2024 – A new research perspective was published in Oncoscience (Volume 11) on May 23, 2024, entitled, “Targeting inflammatory factors for chemoprevention and cancer interception to tackle malignant mesothelioma.”

In this perspective, researchers Joseph R. Testa, Yuwaraj Kadariya, and Joseph S. Friedberg from Fox Chase

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Antibody-drug Conjugates in Gynecologic Cancer



2024-07-12

“We are optimistic that the incorporation of ADCs into the treatment of aggressive tumors and treatment refractory gynecologic cancers will improve quality of life and survival outcomes in our patients.”



BUFFALO, NY - July 12, 2024 – A new editorial paper was published in Oncoscience (Volume 11) on May 20, 2024, entitled, “Entering the golden age for antibody-drug conjugates in gynecologic cancer.”

In this new editorial, researchers Michelle Greenman, Blair McNamara, Levent Mutlu, and

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A Feasibility Study for Salvage Radiation Therapy in Prostate Cancer



2024-06-28

“The deployment of DL segmentation methods in 18F-fluciclovine PET/CT imaging represents an intriguing research direction for precision medicine in salvage prostate cancer care.”



BUFFALO, NY - June 28, 2024 – A new editorial paper was published in Oncoscience (Volume 11) on May 20, 2024, entitled, “Deep learning-assisted lesion segmentation in PET/CT imaging: A feasibility study for salvage radiation therapy in prostate cancer.”

In this new editorial, researchers Richard L.J. Qiu, Chih

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Treatment Options for a Rare Tumor: Primary Hepatic Angiosarcoma



2024-06-21

“[...] PHA is a rare yet aggressive mesenchymal tumor of the liver, which requires a multi-disciplinary approach to achieve the best patient outcomes.”



BUFFALO, NY - June 21, 2024 – A new editorial paper was published in Oncoscience (Volume 11) on May 20, 2024, entitled, “Primary hepatic angiosarcoma: Treatment options for a rare tumor.”

In this new editorial, researchers Gregory L. Guzik and Ankit Mangla from University Hospitals Cleveland Medical Center, University Hospitals Seidman

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Erk5 and Its Potential Applications in Cancer Treatment



2024-06-14

“Elucidating the function of Erk5 in cancer [...] will contribute to a better understanding of cancer pathogenesis and the development of novel therapeutic strategies.”



BUFFALO, NY - June 14, 2024 – A new editorial paper was published in Oncoscience (Volume 11) on May 20, 2024, entitled, “Role of Erk5 expressed in bone marrow mesenchymal stem cells on bone homeostasis and its potential applications in cancer treatment.”

In their new editorial, researchers Tetsuhiro Horie and Eiichi

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Oncoscience Sponsors 2024 Ride for Roswell



2024-06-11

“Impact Journals (Oncoscience's publisher) is sponsoring Team Open Access in the annual cycling event to end cancer: The Ride for Roswell. This fundraiser is hosted by Roswell Park Comprehensive Cancer Center in Buffalo, New York.”

BUFFALO, NY- June 11, 2024 – The Ride for Roswell is one of the nation’s largest cycling events—hosted by Roswell Park Comprehensive Cancer Center—to raise awareness and funds for cancer research and patient care. This charity bike ride, based out of Buffalo, New

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Restoring Our Ubiquitination Machinery to Overcome Cancer Therapy Resistance



2024-06-07

“[...] the identification of ubiquitin-conjugating enzymes like UBE2J1 and the innovative deployment of PROTAC-type androgen receptor degraders are crucial in combating prostate cancer and overcoming therapeutic resistance.”



BUFFALO, NY - June 7, 2024 – A new editorial paper was published in Oncoscience (Volume 11) on May 6, 2024, entitled, “Restoring our ubiquitination machinery to overcome resistance in cancer therapy.”

In this new editorial, researchers Xiaoling Li and Ping Mu from

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PH-binding Motifs as a Platform for Drug Design: Lessons From Protease-activated Receptors (PARs)



2024-05-24

“We have identified binding motifs within the C-tails of PAR1,2&4, indispensable for cancer growth and development.”



BUFFALO, NY - May 24, 2024 – A new editorial paper was published in Oncoscience (Volume 11) on April 25, 2024, entitled, “PH-binding motifs as a platform for drug design: Lessons from protease-activated receptors; PARs.”

While targeted cancer therapy is greatly dependent on specific oncogenic pathways or conferred by genetic alterations, it remains yet challenging and

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The Price of Hope: CAR-T Therapy & Pediatric Leukemia



2024-05-17

“The advancement of novel therapies like CAR-T in relapsed and refractory pediatric B-ALL is truly a beacon of hope for children and young adults with a previously dismal prognosis.”



BUFFALO, NY - May 17, 2024 – A new editorial paper was published in Oncoscience (Volume 11) on April 25, 2024, entitled, “The price of hope: CAR-T therapy in pediatric leukemia.”

We stand at the crossroads of medical innovation, where cutting-edge scientific discoveries intersect with the resilience of

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Oncoscience at SSP 46th Annual Meeting



2024-05-13




BUFFALO, NY- May 13, 2024 – Impact Journals publishes scholarly journals in the biomedical sciences with a focus on all areas of cancer and aging research. Oncoscience is one of the most prominent journals published by Impact Journals.

Impact Journals is proud to participate as an exhibitor at the Society for Scholarly Publishing (SSP) 46th Annual Meeting, which convenes in Boston, Massachusetts, at the Westin Boston Seaport District from May 29–31, 2024. This year, the SSP Annual

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Editorial: Therapeutic Opportunities for Hypermutated Urothelial Carcinomas Beyond Immunotherapy



2024-05-10

“These results argue that combinations based on immunotherapy may also provide an opportunity for targeting urothelial cancers with low TMB, and provide efficacy superior to classic chemotherapy.”



BUFFALO, NY - May 10, 2024 – A new editorial paper was published in Oncoscience (Volume 11) on April 25, 2024, entitled, “Therapeutic opportunities for hypermutated urothelial carcinomas beyond immunotherapy.”

In this new editorial, researcher Ioannis A. Voutsadakis from Sault Area Hospital

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Exploring Oncogenic Driver Molecular Alterations in Hispanic/Latin American Cancer Patients



2024-05-03

“[...] this editorial underscores the complex molecular diagnosis landscape of cancer in the [Latin American] population.”



BUFFALO, NY - May 03, 2024 – A new editorial paper was published in Oncoscience (Volume 11) on April 22, 2024, entitled, “Exploring oncogenic driver molecular alterations in Hispanic/Latin American cancer patients: A call for enhanced molecular understanding.”

In this editorial, researcher Rafael Parra-Medina from Fundación Universitaria de Ciencias de la Salud

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Oncoscience at AACR Annual Meeting 2024



2024-03-11

BUFFALO, NY- March 11, 2024 – Impact Journals publishes scholarly journals in the biomedical sciences with a focus on all areas of cancer and aging research. Oncoscience is one of the most prominent journals published by Impact Journals.

Impact Journals will be participating as an exhibitor at the American Association for Cancer Research (AACR) Annual Meeting 2024 from April 5-10 at the San Diego Convention Center in San Diego, California. This year, the AACR meeting theme is “Inspiring

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A Very Long, Winding Road: Developing Novel Therapeutics for Metastatic Tumors



2024-02-23

“Given that the MET inhibitor capmatinib caused a remarkable response in Dr. Blagosklonny, a pertinent question remains as to why he was not treated with ‘preemptive drug combinations’ [...]”



BUFFALO, NY - February 23, 2024 – A new editorial paper was published in Oncoscience (Volume 11) on February 9, 2024, entitled, “A very long and winding road: developing novel therapeutics for metastatic tumors.”

In this editorial, researcher Paul Dent from the Department of Biochemistry and

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IPIAD: An Augmentation to Standard Treatment of PDAC Using Five Repurposed Drugs



2024-02-09

“This paper presents the rationale for adding five already approved and marketed generic drugs from general medical practice to the current standard current first line chemotherapy for pancreatic ductal adenocarcinoma (PDAC).”



BUFFALO, NY - February 9, 2024 – A new research perspective was recently published in Oncoscience (Volume 11) on February 7, 2024, entitled, “IPIAD- an augmentation regimen added to standard treatment of pancreatic ductal adenocarcinoma using already-marketed

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Dr. Blagosklonny's Battle With Cancer (Part 1)



2024-01-22

“Diagnosed with numerous metastases of lung cancer in my brain in January 2023, I felt compelled to accomplish a mission.”



BUFFALO, NY- January 22, 2024 – On January 3, 2024, Mikhail V. Blagosklonny M.D., Ph.D., from Roswell Park Comprehensive Cancer Center published a new brief report in Oncoscience (Volume 11), entitled, “My battle with cancer. Part 1.

“In January 2023, diagnosed with numerous metastases of lung cancer in my brain, I felt that I... continue reading >>

Mutational Signatures of Cancer: Can Passengers Set a Direction for Prognosis?



2024-01-19

“[...] mutational signatures are not only genomic noise of passenger mutations, but they provide etiological and biological information on carcinogenesis.”



BUFFALO, NY- January 19, 2024 – A new editorial paper was recently published in Oncoscience (Volume 10), by researcher Peeter Karihtala from the University of Helsinki and University Hospital Comprehensive Cancer Center, entitled, “The mutational signatures of cancer: can passengers set a direction for prognosis?

In the early

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Pazopanib in EWSR1-NFATC2 Translocation-associated Bone Sarcoma



2024-01-12

“Pazopanib is a multi-kinase inhibitor that is currently approved for treatment of advanced renal cell carcinoma and chemotherapy-refractory soft tissue sarcoma.”



BUFFALO, NY- January 12, 2024 – A new case report was recently published in Oncoscience (Volume 10) on September 20, 2023, entitled, “Activity of pazopanib in EWSR1-NFATC2 translocation-associated bone sarcoma.”

Pazopanib, a multi-kinase VEGF inhibitor, is currently FDA approved for advanced renal cell carcinoma and advanced

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Lipiodol: From Intrusion to Exile From the Tumor Microenvironment



2024-01-05

“[...] this study proposed that the size of the tumor [...] and lipiodol washout rate could predict the outcome of cTACE in patients with metastatic liver tumors.”



BUFFALO, NY- January 5, 2024 – An editorial paper was recently published in Oncoscience (Volume 10) on August 17, 2023, entitled, “Lipiodol: from intrusion until exile from the tumor microenvironment.”

In this new editorial, researchers Sheena Anand, Jean-François Geschwind, Vahid Etezadi, and Nariman Nezami from the Univer

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