Oncoscience

Press Release Archive

Research Validates Laboratory Model for Studying High-Grade Serous Ovarian Cancer

December 23, 2025
“The insights gained from this study not only validate OVCAR3 as a representative model for HGSOC, but also provide a foundation for developing targeted therapeutic strategies.”BUFFALO, NY — December 23, 2025 — A new research paper was published in Volume 12 of Oncoscience on October 14, 2025, titled “Bridging clinical insight and laboratory model in high-grade serous ovarian carcinoma (HGSOC) using DNA sequencing-based profiling of TP53.”In this study, Faisal Iqbal from the... continue reading >>

Systematic Review Links Pancreatic Cancer Surgery to Postoperative Diabetes Risk

December 19, 2025
“The development of NODM after partial pancreatic resections for pancreatic adenocarcinoma is a severe complication that requires prompt diagnosis, careful monitoring and systematic management.” BUFFALO, NY — December 19, 2025 — A new review was published in Volume 12 of Oncoscience on December 8, 2025, titled "Incidence and risk factors for new-onset diabetes mellitus (NODM) in post-pancreatectomy patients diagnosed with pancreatic adenocarcinoma (PAC): A... continue reading >>

Radiation-Induced Cellular Changes May Mimic Cancer Recurrence in Pap Smears

December 10, 2025
“The present case highlights the need for heightened awareness of post-radiation cytology in clinical practice.” BUFFALO, NY — December 10, 2025 — A new case report was published in Volume 12 of Oncoscience on November 19, 2025, titled “Deciphering radiation effects in pap smears: A case report and review of challenges.” In this report, Gunvanti Rathod, Monica Mishra, Alisha Khan, and Mishu Mangla from AIIMS Bibinagar describe a case of a... continue reading >>

Sudden Cardiac Death Risk Falls in Colorectal Cancer, But Disparities Persist

December 4, 2025
“Persistent discrepancies by gender, race, and geography underline the importance of individualized cardio-oncology surveillance, equitable preventative initiatives, and focused public health interventions.” BUFFALO, NY — December 4, 2025 — A new research paper was published in Volume 12 of Oncoscience on November 7, 2025, titled “Temporal trends and disparities in sudden cardiac death among colorectal cancer patients: A nationwide study.” In... continue reading >>

Gut Microbiome Connects Obesity to Cancer, Impacting Public Health

November 24, 2025
“The gut microbiome functions as both a biomarker and therapeutic target across metabolic and neoplastic diseases.” BUFFALO, NY — November 24, 2025 — A new review was published in Volume 12 of Oncoscience on November 7, 2025, titled “From obesity to cancer: Gut microbiome mechanisms, biomarkers, and U.S. public health strategies.” This review, led by first author Hashim Muhammad Moseeb and corresponding author Zahoor Kamran from the University... continue reading >>

Lymphoma and Targeted Therapy: Resistance Mechanisms and Future Solutions

November 13, 2025
“This review synthesizes current evidence to inform clinical decision-making and outlines future directions for durable, personalized lymphoma care.” BUFFALO, NY — November 13, 2025 — A new review was published in Volume 12 of Oncoscience on October 13, 2025, titled "Targeted therapies and resistance mechanisms in lymphoma: Current landscape and emerging solutions." In this article by Bishal Tiwari, Roshan Afshan and Shruthi Sridhar, from Nassau University... continue reading >>

Trastuzumab Deruxtecan Shows Positive Results in Rare Breast Cancer with Brain Metastasis

November 5, 2025
“This solid evidence is seemingly leading into a new and groundbreaking BC treatment era.” BUFFALO, NY — November 5, 2025 — A new case report was published in Volume 12 of Oncoscience on October 9, 2025, titled "Metastatic breast cancer with leptomeningeal carcinomatosis treated with trastuzumab deruxtecan – a case report." In this report, Cristiana Honrado Martins, José Miguel Rocha, Catarina Portela, Ricardo Fernandes, and Cláudia Caeiro from Hospital de... continue reading >>

Rare Vulvar Cyst Case Report Sheds Light on Diagnostic Challenges

October 30, 2025
“This case emphasizes the importance of considering rare vulvar mucinous cysts in the differential diagnosis of asymptomatic vulvar masses.” BUFFALO, NY — October 30, 2025 — A new case report was published in Volume 12 of Oncoscience on October 9, 2025, titled "Vulvar mucinous cyst mimicking common lesions with concurrent multiple bartholin cysts in a reproductive-age woman: A rare case report and review of literature." Naina Kumar, Immanuel Pradeep, Banka Sai... continue reading >>

Rare Case of Pancreatic Hodgkin Lymphoma Highlights Importance of Early Diagnosis

October 22, 2025
“This case underscores the importance of obtaining tissue diagnosis in the setting of a pancreatic mass before embarking on definitive treatment.” BUFFALO, NY — October 22, 2025 — A new case report was published in Volume 12 of Oncoscience on October 6, 2025, titled "A peculiar case of primary lymphoma of pancreas: A rare presentation of Hodgkin lymphoma." In this report led by first author Osama Mohiuddin from Ascension At Agnes Healthcare, with corresponding... continue reading >>

Epithelioid Hemangioendothelioma: Rare Vascular Tumor Mimics Common Hematoma

October 16, 2025
“This report aims to highlight the diagnostic nuances, potential for misinterpretation, and therapeutic dilemmas associated with EHE, thereby reinforcing the need for vigilance in evaluating seemingly “low-risk” atypical subcutaneous swellings.” BUFFALO, NY — October 16, 2025 — A new case report was published in Volume 12 of Oncoscience on October 3, 2025, titled "Epithelioid hemangioendothelioma: A rare mimicker of post-traumatic hematoma." The... continue reading >>

Male Infertility in Indian Men Linked to Lifestyle Choices and Hormonal Imbalances

October 10, 2025
“Lifestyle habits and hormonal imbalances significantly affect the fertility of men.” BUFFALO, NY — October 10, 2025 — A new research paper was published in Volume 12 of Oncoscience on September 30, 2025, titled "Lifestyle and hormonal factors affecting semen quality and sperm DNA integrity: A cross-sectional study." In this study, Saniya Imtiyaz Chamanmalik, Rajendra B. Nerli, and Pankaja Umarane from KLE Academy of Higher Education and Research and Dr. D. Y.... continue reading >>

Multiple Strokes Lead to Hidden Colorectal Cancer Diagnosis in Rare Case

September 24, 2025
“This case highlights the importance of early consideration of occult malignancy in cryptogenic embolic events, supporting comprehensive oncologic evaluation for unexplained hypercoagulable states.” BUFFALO, NY — September 24, 2025 — A new case report was published in Volume 12 of Oncoscience on September 15, 2025, titled "When strokes reveal a hidden malignancy: An atypical case of metastatic colorectal cancer with extensive thromboembolism." In this case... continue reading >>

Rare Uterine Tumors with Pregnancy-Like Features Linked to Poor Survival

September 16, 2025
“Measurement of pre-operative β-hCG may be considered in all cases of endometrial carcinomas and sarcomas, and if found elevated, immunohistochemical examination with β-hCG should be carried out.” BUFFALO, NY — September 16, 2025 — A new review was published in Volume 12 of Oncoscience on September 4, 2025, titled “Prognostic significance of trophoblastic differentiation and β-hCG secretion in somatic malignancies of uterine corpus: A... continue reading >>

Adult Fibrosarcoma Case Report Shows Importance of Early Diagnosis and Targeted Therapy

September 9, 2025
“Adult fibrosarcoma is a rare and highly aggressive malignancy requiring precise diagnosis and multimodal treatment.” BUFFALO, NY — September 9, 2025 — A new case report was published in Volume 12 of Oncoscience on September 4, 2025, titled "Adult fibrosarcoma: From clinical challenges to cutting-edge innovations." In this case report, Reshmi Sultana from the All India Institute of Medical Sciences, Bibinagar, India, and Suryadevara Sailaja from the Alluri... continue reading >>

Majority of Oncology Staff at Moroccan Cancer Institute Affected by Burnout

August 28, 2025
“Burnout is highly prevalent among oncology healthcare professionals in Morocco, particularly among young female nurses.” BUFFALO, NY — August 28, 2025 — A new research paper was published in Volume 12 of Oncoscience on July 31, 2025, titled "Burnout among oncology nurses and technicians in Morocco: Prevalence, risk factors, and structural equation modeling." In this study, Imane Errami, Saber Boutayeb, and Hassan Errihani from the Faculty of Medicine and... continue reading >>

Unusual Case of Rare Ovarian Tumor Mimicking Pregnancy with Successful Treatment Outcome

August 14, 2025
“Our case illustrates the classic features of NGOC, including significant bleeding, markedly elevated ?-hCG levels, and a unilateral adnexal mass on imaging.” BUFFALO, NY — August 14, 2025 — A new case report was published in Volume 12 of Oncoscience on July 28, 2025, titled "A rare case of pure non-gestational ovarian choriocarcinoma: Diagnostic mimicry and management strategies." This report, led by Naina Kumar from the All India Institute of Medical Sciences,... continue reading >>

Benign Uterine Tumor Resembling Cancer Highlights Diagnostic Challenges

July 18, 2025
“This case highlights that lipoleiomyomas can present many years after attaining menopause.” BUFFALO, NY — July 18, 2025 — A new case report was published in Volume 12 of Oncoscience on July 2, 2025, titled “Navigating diagnostic complexity: A case report on uterine lipoleiomyoma, unveiling its benign nature amidst characteristics resembling liposarcoma." In this report, first author Seetu Palo, corresponding author Mishu Mangla and colleagues from the All... continue reading >>

Genetic Testing Offers a Cost-Effective Tool for Early Prostate Cancer Detection

June 18, 2025
“Our findings further underscore the relevance of RFLP-based genotyping as an affordable substitute for NGS, in light of limited accessibility in many resource-limited settings.” BUFFALO, NY — June 18, 2025 — A new research paper was published in Volume 12 of Oncoscience on May 26, 2025, titled “Integrating molecular diagnostics for early prostate cancer detection.” In this study, led by Pankaja B. Umarane from KLES Dr. Prabhakar Kore Hospital and MRC and KLE Academy... continue reading >>

Rare Ovarian Tumor Discovered During Postmenopausal Vault Prolapse Evaluation

June 13, 2025
“The incidental discovery of a pure SCT in an atrophic ovary during pelvic surgery in a postmenopausal woman is exceedingly rare.” BUFFALO, NY — June 13, 2025 — A new case report was published in Volume 12 of Oncoscience on May 22, 2025, titled “A rare case: Pure Sertoli cell tumor uncovered in atrophic ovary during postmenopausal vault prolapse evaluation." In this case report, corresponding author Naina Kumar from the All India Institute of Medical Sciences... continue reading >>

Oncoscience Sponsors Open Access Team in 2025 Ride for Roswell

June 10, 2025
“Impact Journals, publisher of Oncoscience, is once again proudly sponsoring the Open Access Team in the annual Ride for Roswell.” BUFFALO, NY — June 10, 2025 — The Ride for Roswell, one of the USA’s largest cycling events supporting cancer research, returns to Buffalo on Saturday, June 28, 2025. Hosted annually by Roswell Park Comprehensive Cancer Center, this community-wide event brings together riders, volunteers, and supporters to raise funds... continue reading >>

25-Year Review Highlights Stomach Cancer-Fighting Potential of Brazilian Plants

May 22, 2025
"Although Brazilian plant species show promising potential as therapeutic agents in SC, the available studies are still scarce." BUFFALO, NY – May 22, 2025 – A new review was published in Volume 12 of Oncoscience on May 8, 2025, titled “The chemopreventive effects of native Brazilian plants on stomach cancer: A review of the last 25 years." The study led by first author Iara Lopes Lemos and corresponding author Mario Roberto Marostica Junior from the University of Campinas... continue reading >>

Immune Checkpoint Inhibitors Significantly Increase Myocarditis Risk in NSCLC Patients

May 16, 2025
"Clinicians should counsel patients regarding myocarditis risk, implement baseline and serial cardiac evaluations for at least six months following ICI initiation, and maintain a low threshold for cardiology referral upon symptom onset." BUFFALO, NY – May 16, 2025 – A new editorial was published in Volume 12 of Oncoscience on May 2, 2025, titled "Immune checkpoint inhibitors and myocarditis: Lessons from a nationwide cohort study." In this editorial, Bishal Tiwari from Nassau... continue reading >>

Oncoscience Participation at SSP 47th Annual Meeting in Baltimore

May 5, 2025
Impact Journals is pleased to participate as an exhibitor at the Society for Scholarly Publishing (SSP) 47th Annual Meeting from May 28–30, 2025, in Baltimore, Maryland. BUFFALO, NY – May 5, 2025 – Impact Journals (Oncoscience’s publisher) is pleased to announce its participation as an exhibitor at the upcoming Society for Scholarly Publishing (SSP) 47th Annual Meeting. The event will take place from May 28-30, 2025, in Baltimore, Maryland. Attendees are invited to visit... continue reading >>

Rare Combination of Ovarian Tumors Found in One Patient

April 4, 2025
“This case underscores the rare coexistence of serous cystadenofibroma in one ovary and collision features involving serous and mucinous cysts in the contralateral ovary, a combination scarcely reported in the literature.” BUFFALO, NY — April 4, 2025— A new case report was publishe d in Oncoscience’s Volume 12 on March 31, 2025, titled “Cystadenofibroma and contralateral collision lesions: A unique ovarian case report.” Authored by Dr. Naina Kumar and... continue reading >>

Oncoscience to Participate at the AACR Annual Meeting 2025

March 17, 2025
Impact Journals is proud to participate in the American Association for Cancer Research (AACR) Annual Meeting 2025, taking place April 25-30 in Chicago, Illinois. BUFFALO, NY – March 17, 2025 – Impact Journals (Oncoscience’s publisher) is pleased to announce its participation as an exhibitor at the upcoming American Association for Cancer Research (AACR) Annual Meeting 2025. The meeting is scheduled for April 25-30, 2025, at the McCormick Place Convention Center in Chicago,... continue reading >>

Rare Uterine Condition Mimics Cancer in Postmenopausal Woman

February 19, 2025
“This case highlights an important variant of Adenomyosis that potentially mimics an invasive uterine neoplasm.” BUFFALO, NY - February 19, 2025 – A new case report was published in Oncoscience's Volume 12 on February 10, 2025, titled “Diffuse cystic adenomyosis simulating invasive uterine neoplasm on imaging: A postmenopausal diagnostic perplexity!” Researchers Anusha Devalla, Mishu Mangla, Krishna Ramavath, Shailaja Prabhala, Naina Kumar, and Aparna... continue reading >>

Severe Osteoporosis as a Manifestation of Systemic Mastocytosis

February 13, 2025
“This report highlights the diagnostic challenges of SM, emphasize its underrecognized role in osteoporosis and fragility fractures, and advocates for its consideration in patients with unexplained skeletal abnormalities.” BUFFALO, NY - February 13, 2025 – A new case report was published in Oncoscience's Volume 12 on February 4, 2025, titled “Breaking point: Systemic mastocytosis manifesting as severe osteoporosis.” First author Areti Kalfoutzou, and... continue reading >>

Cervical Cancer: Maternal, Delivery & Neonatal Outcomes Study

February 5, 2025
“Our study aims to address the knowledge gap regarding the outcomes of cervical cancer on both maternal and fetal health.” BUFFALO, NY - February 5, 2025 – A new research paper was published in Oncoscience's Volume 12 on January 20, 2025, titled, “Maternal, delivery and neonatal outcomes in women with cervical cancer. A study of a population database.” In this large study, researchers Aaron Samuels, Ahmad Badeghiesh, Haitham Baghlaf, and Michael H. Dahan... continue reading >>

How Pomalidomide Boosts the Immune System to Fight Multiple Myeloma

January 23, 2025
“It has been postulated that the clinical benefit of adding POM results from enhanced immunocompetency.” BUFFALO, NY - January 23, 2025 – A new editorial was published in Oncoscience's Volume 12 on January 14, 2025, titled, “Pomalidomide improved immune profiles in myeloma.” The editorial by researchers Hannah Seah, Vaishnavi Reddy Bade, Lakshmi Bhavani Potluri, Srikanth Talluri, and Rao H. Prabhala from Dana-Farber Cancer Institute, VA Boston Healthcare... continue reading >>

Targeting Carbohydrate Metabolism in Colorectal Cancer: Synergy of Therapies

November 15, 2024
“This commentary will discuss what is known about such combinatorial treatments, including potential mechanisms and future protocols.” BUFFALO, NY - November 15, 2024 – A new review was published in Oncoscience (Volume 11) on November 12, 2024, entitled, “Targeting carbohydrate metabolism in colorectal cancer - synergy between DNA-damaging agents, cannabinoids, and intermittent serum starvation.” As highlighted by the authors in the abstract of this... continue reading >>

Tribute to Dr. Mikhail (Misha) Blagosklonny

October 22, 2024
It is with great sadness and heavy heart that we announce the recent passing of Dr. Mikhail (Misha) V. Blagosklonny, our beloved Editor-in-Chief. Misha succumbed to metastatic lung cancer after a courageous battle. Dr. Blagosklonny will be remembered as a brilliant and extraordinary scientist who dedicated his life to science. He was a visionary thinker, who made highly original contributions to cancer and aging research that were often ahead of their time. Dr. Blagosklonny was born into a... continue reading >>

Long-lasting Immunotherapy Response in Stage IV Lung Cancer with Brain Metastasis

October 18, 2024
“In the last decade, immunotherapy agents changed the treatment landscape for Non-Small Cell Lung Cancer (NSCLC).” BUFFALO, NY - October 18, 2024 – A new case report was published in Oncoscience (Volume 11) on October 8, 2024, entitled, “Complete and long-lasting response to immunotherapy in a stage IV non-small cell lung cancer with brain metastasis.” As highlighted in the abstract of this report, approximately 20% of lung cancer patients have brain... continue reading >>

Challenge of Weight Gain in Hormone Receptor-Positive Breast Cancer

September 27, 2024
“This study highlighted patterns of weight gain among early-stage HR+ breast cancer, especially among those with healthy BMI or overweight after cancer diagnosis.” BUFFALO, NY - September 27, 2024 – A new editorial was published in Oncoscience (Volume 11) on September 23, 2024, entitled, “The challenge of weight gain in hormone receptor-positive breast cancer.” As introduced in this editorial, obesity is associated with an increased risk of developing... continue reading >>

Functional Information Offers Individualized Adaptive Cancer Therapies

August 30, 2024
“Functional information is an emerging research area that needs participation from all fields of precision medicine.” BUFFALO, NY - August 30, 2024 – A new editorial was published in Oncoscience (Volume 11) on July 19, 2024, entitled, “Functional information offers individualized adaptive cancer therapies.” As introduced in this editorial, the Oxford Computer Science Dictionary offers both general and technical definitions of information. Generally,... continue reading >>

Retrotransposon DNA Zip Code for Myeloma Cell Internalization

August 9, 2024
“GT is a fascinating evolutionary phenomenon observed in lower species and humans, albeit with differing impacts and mechanisms.” BUFFALO, NY - August 09, 2024 – A new editorial was published in Oncoscience (Volume 11) on July 13, 2024, entitled, “Unveiling retrotransposon-derived DNA zip code for myeloma cell internalization.” The complex interplay between extracellular genetic material and the tumor's genetic landscape presents a significant... continue reading >>

Targeting Factors for Chemoprevention and Cancer Interception to Tackle Mesothelioma

July 19, 2024
“In this research perspective, we review the current state of chemoprevention and cancer interception progress in asbestos-induced mesothelioma.” BUFFALO, NY - July 19, 2024 – A new research perspective was published in Oncoscience (Volume 11) on May 23, 2024, entitled, “Targeting inflammatory factors for chemoprevention and cancer interception to tackle malignant mesothelioma.” In this perspective, researchers Joseph R. Testa, Yuwaraj Kadariya, and... continue reading >>

Antibody-drug Conjugates in Gynecologic Cancer

July 12, 2024
“We are optimistic that the incorporation of ADCs into the treatment of aggressive tumors and treatment refractory gynecologic cancers will improve quality of life and survival outcomes in our patients.” BUFFALO, NY - July 12, 2024 – A new editorial paper was published in Oncoscience (Volume 11) on May 20, 2024, entitled, “Entering the golden age for antibody-drug conjugates in gynecologic cancer.” In this new editorial, researchers Michelle Greenman,... continue reading >>

A Feasibility Study for Salvage Radiation Therapy in Prostate Cancer

June 28, 2024
“The deployment of DL segmentation methods in 18F-fluciclovine PET/CT imaging represents an intriguing research direction for precision medicine in salvage prostate cancer care.” BUFFALO, NY - June 28, 2024 – A new editorial paper was published in Oncoscience (Volume 11) on May 20, 2024, entitled, “Deep learning-assisted lesion segmentation in PET/CT imaging: A feasibility study for salvage radiation therapy in prostate cancer.” In this new editorial,... continue reading >>

Treatment Options for a Rare Tumor: Primary Hepatic Angiosarcoma

June 21, 2024
“[...] PHA is a rare yet aggressive mesenchymal tumor of the liver, which requires a multi-disciplinary approach to achieve the best patient outcomes.” BUFFALO, NY - June 21, 2024 – A new editorial paper was published in Oncoscience (Volume 11) on May 20, 2024, entitled, “Primary hepatic angiosarcoma: Treatment options for a rare tumor.” In this new editorial, researchers Gregory L. Guzik and Ankit Mangla from University Hospitals Cleveland Medical... continue reading >>

Erk5 and Its Potential Applications in Cancer Treatment

June 14, 2024
“Elucidating the function of Erk5 in cancer [...] will contribute to a better understanding of cancer pathogenesis and the development of novel therapeutic strategies.” BUFFALO, NY - June 14, 2024 – A new editorial paper was published in Oncoscience (Volume 11) on May 20, 2024, entitled, “Role of Erk5 expressed in bone marrow mesenchymal stem cells on bone homeostasis and its potential applications in cancer treatment.” In their new editorial,... continue reading >>

Oncoscience Sponsors 2024 Ride for Roswell

June 11, 2024
“Impact Journals (Oncoscience's publisher) is sponsoring Team Open Access in the annual cycling event to end cancer: The Ride for Roswell. This fundraiser is hosted by Roswell Park Comprehensive Cancer Center in Buffalo, New York.” BUFFALO, NY- June 11, 2024 – The Ride for Roswell is one of the nation’s largest cycling events—hosted by Roswell Park Comprehensive Cancer Center—to raise awareness and funds for cancer research and patient care. This charity... continue reading >>

Restoring Our Ubiquitination Machinery to Overcome Cancer Therapy Resistance

June 7, 2024
“[...] the identification of ubiquitin-conjugating enzymes like UBE2J1 and the innovative deployment of PROTAC-type androgen receptor degraders are crucial in combating prostate cancer and overcoming therapeutic resistance.” BUFFALO, NY - June 7, 2024 – A new editorial paper was published in Oncoscience (Volume 11) on May 6, 2024, entitled, “Restoring our ubiquitination machinery to overcome resistance in cancer therapy.” In this new editorial,... continue reading >>

PH-binding Motifs as a Platform for Drug Design: Lessons From Protease-activated Receptors (PARs)

May 24, 2024
“We have identified binding motifs within the C-tails of PAR1,2&4, indispensable for cancer growth and development.” BUFFALO, NY - May 24, 2024 – A new editorial paper was published in Oncoscience (Volume 11) on April 25, 2024, entitled, “PH-binding motifs as a platform for drug design: Lessons from protease-activated receptors; PARs.” While targeted cancer therapy is greatly dependent on specific oncogenic pathways or conferred by genetic... continue reading >>

The Price of Hope: CAR-T Therapy & Pediatric Leukemia

May 17, 2024
“The advancement of novel therapies like CAR-T in relapsed and refractory pediatric B-ALL is truly a beacon of hope for children and young adults with a previously dismal prognosis.” BUFFALO, NY - May 17, 2024 – A new editorial paper was published in Oncoscience (Volume 11) on April 25, 2024, entitled, “The price of hope: CAR-T therapy in pediatric leukemia.” We stand at the crossroads of medical innovation, where cutting-edge scientific discoveries... continue reading >>

Oncoscience at SSP 46th Annual Meeting

May 13, 2024
BUFFALO, NY- May 13, 2024 – Impact Journals publishes scholarly journals in the biomedical sciences with a focus on all areas of cancer and aging research. Oncoscience is one of the most prominent journals published by Impact Journals. Impact Journals is proud to participate as an exhibitor at the Society for Scholarly Publishing (SSP) 46th Annual Meeting, which convenes in Boston, Massachusetts, at the Westin Boston Seaport District from May 29–31, 2024. This year, the... continue reading >>

Editorial: Therapeutic Opportunities for Hypermutated Urothelial Carcinomas Beyond Immunotherapy

May 10, 2024
“These results argue that combinations based on immunotherapy may also provide an opportunity for targeting urothelial cancers with low TMB, and provide efficacy superior to classic chemotherapy.” BUFFALO, NY - May 10, 2024 – A new editorial paper was published in Oncoscience (Volume 11) on April 25, 2024, entitled, “Therapeutic opportunities for hypermutated urothelial carcinomas beyond immunotherapy.” In this new editorial, researcher Ioannis A.... continue reading >>

Exploring Oncogenic Driver Molecular Alterations in Hispanic/Latin American Cancer Patients

May 3, 2024
“[...] this editorial underscores the complex molecular diagnosis landscape of cancer in the [Latin American] population.” BUFFALO, NY - May 03, 2024 – A new editorial paper was published in Oncoscience (Volume 11) on April 22, 2024, entitled, “Exploring oncogenic driver molecular alterations in Hispanic/Latin American cancer patients: A call for enhanced molecular understanding.” In this editorial, researcher Rafael Parra-Medina from Fundación... continue reading >>

Oncoscience at AACR Annual Meeting 2024

March 11, 2024
BUFFALO, NY- March 11, 2024 – Impact Journals publishes scholarly journals in the biomedical sciences with a focus on all areas of cancer and aging research. Oncoscience is one of the most prominent journals published by Impact Journals. Impact Journals will be participating as an exhibitor at the American Association for Cancer Research (AACR) Annual Meeting 2024 from April 5-10 at the San Diego Convention Center in San Diego, California. This year, the AACR meeting theme is... continue reading >>

A Very Long, Winding Road: Developing Novel Therapeutics for Metastatic Tumors

February 23, 2024
“Given that the MET inhibitor capmatinib caused a remarkable response in Dr. Blagosklonny, a pertinent question remains as to why he was not treated with ‘preemptive drug combinations’ [...]” BUFFALO, NY - February 23, 2024 – A new editorial paper was published in Oncoscience (Volume 11) on February 9, 2024, entitled, “A very long and winding road: developing novel therapeutics for metastatic tumors.” In this editorial, researcher Paul Dent... continue reading >>

IPIAD: An Augmentation to Standard Treatment of PDAC Using Five Repurposed Drugs

February 9, 2024
“This paper presents the rationale for adding five already approved and marketed generic drugs from general medical practice to the current standard current first line chemotherapy for pancreatic ductal adenocarcinoma (PDAC).” BUFFALO, NY - February 9, 2024 – A new research perspective was recently published in Oncoscience (Volume 11) on February 7, 2024, entitled, “IPIAD- an augmentation regimen added to standard treatment of pancreatic ductal adenocarcinoma... continue reading >>

Dr. Blagosklonny's Battle With Cancer (Part 1)

January 22, 2024
“Diagnosed with numerous metastases of lung cancer in my brain in January 2023, I felt compelled to accomplish a mission.” BUFFALO, NY- January 22, 2024 – On January 3, 2024, Mikhail V. Blagosklonny M.D., Ph.D., from Roswell Park Comprehensive Cancer Center published a new brief report in Oncoscience (Volume 11), entitled, “ continue reading >>

Mutational Signatures of Cancer: Can Passengers Set a Direction for Prognosis?

January 19, 2024
“[...] mutational signatures are not only genomic noise of passenger mutations, but they provide etiological and biological information on carcinogenesis.” BUFFALO, NY- January 19, 2024 – A new editorial paper was recently published in Oncoscience (Volume 10), by researcher Peeter Karihtala from the University of Helsinki and University Hospital Comprehensive Cancer Center, entitled, “The mutational signatures of cancer: can passengers set a direction for... continue reading >>

Pazopanib in EWSR1-NFATC2 Translocation-associated Bone Sarcoma

January 12, 2024
“Pazopanib is a multi-kinase inhibitor that is currently approved for treatment of advanced renal cell carcinoma and chemotherapy-refractory soft tissue sarcoma.” BUFFALO, NY- January 12, 2024 – A new case report was recently published in Oncoscience (Volume 10) on September 20, 2023, entitled, “Activity of pazopanib in EWSR1-NFATC2 translocation-associated bone sarcoma.” Pazopanib, a multi-kinase VEGF inhibitor, is currently FDA approved for advanced... continue reading >>

Lipiodol: From Intrusion to Exile From the Tumor Microenvironment

January 5, 2024
“[...] this study proposed that the size of the tumor [...] and lipiodol washout rate could predict the outcome of cTACE in patients with metastatic liver tumors.” BUFFALO, NY- January 5, 2024 – An editorial paper was recently published in Oncoscience (Volume 10) on August 17, 2023, entitled, “Lipiodol: from intrusion until exile from the tumor microenvironment.” In this new editorial, researchers Sheena Anand, Jean-François Geschwind, Vahid... continue reading >>

Squamous Cell Carcinoma of the Oral Cavity: Treatment and Distant Metastatic Behavior

December 22, 2023
“[...] atypical complaints and symptoms outside the head and neck region can indicate (distant) metastasis [...]” BUFFALO, NY- December 22, 2023 – A new research perspective was published in Oncoscience (Volume 10) on August 14, 2023, entitled, “Squamous cell carcinoma of the oral cavity – follow up treatment and distant metastatic behavior.” Up to 90% of tumors in the head and neck region are squamous cell carcinomas (SCC). SCC can develop in... continue reading >>

Insights in Blood-Based Liquid Biopsies for Prostate Cancer Interrogation

December 8, 2023
“In the United States, 288,300 new cases of prostate cancer are estimated for 2023 [...]” BUFFALO, NY- December 8, 2023 – A new research perspective was published in Oncoscience (Volume 10) on November 30, 2023, entitled, “Evolving insights in blood-based liquid biopsies for prostate cancer interrogation.” During the last decade, blood sampling of cancer patients aimed at analyzing the presence of cells, membrane-bound vesicles, or molecules released by... continue reading >>

Potential Pitfalls When Using the Cre-LoxP System in Cancer Research

December 1, 2023
“One limitation [of Cre-LoxP], the focus of this editorial, is the potential loss of fidelity of Cre recombinase expression especially in the context of modeling cancer in mice.” BUFFALO, NY- December 1, 2023 – A new editorial paper was published in Oncoscience (Volume 10) on November 14, 2023, entitled, “Be mindful of potential pitfalls when using the Cre-LoxP system in cancer research.” In this new editorial, researchers Piotr Czarnota and Jaroslaw... continue reading >>

DDX53: A Potential Early Esophageal Cancer Antigen

November 17, 2023
“In this ESCA study, the possibility of an immune response that selected for tumor cells lacking the DDX53 CTA is discussed.” BUFFALO, NY- November 17, 2023 – A new research paper was published in Oncoscience (Volume 10) on November 10, 2023, entitled, “An immunoinformatics assessment of the cancer testis antigen, DDX53, as a potential early esophageal cancer antigen.” T-lymphocytes have been implicated in facilitating a pro-inflammatory,... continue reading >>

Management of Recurrent Gastrointestinal Cancer with Ripretinib and Surgery

November 3, 2023
“The patient was managed with ripretinib and surgical resection of progressing lesions at multiple time points which led to extended clinical benefit.” BUFFALO, NY- November 3, 2023 – A new case report was published in Oncoscience (Volume 10) on September 20, 2023, entitled, “Multi-disciplinary management of recurrent gastrointestinal stromal tumor harboring KIT exon 11 mutation with the switch-control kinase inhibitor ripretinib and... continue reading >>

Diagnosis and Management of Postoperative Wound Infections in the Head and Neck

October 20, 2023
“The majority of wound infections often manifest themselves immediately postoperatively, so close followup should take place […]” BUFFALO, NY- October 20, 2023 – A new research perspective was published in Oncoscience (Volume 10) on October 4, 2023, entitled, “Diagnosis and management of postoperative wound infections in the head and neck region.” In everyday clinical practice at a department for oral and maxillofacial surgery, a large... continue reading >>

Lurbinectedin for Neuroendocrine Tumors (NETs)

October 6, 2023
“Several ongoing trials hope to further elucidate the role of lurbinectedin in highgrade neuroendocrine neoplasms […]” BUFFALO, NY- October 6, 2023 – A new editorial paper was published in Oncoscience (Volume 10) on June 14, 2023, entitled, “Lurbinectedin, a DNA minor groove inhibitor for neuroendocrine neoplasms beyond small cell lung cancer.” In their new editorial, researchers Deepak Bhamidipati and Vivek Subbiah from the Sarah Cannon... continue reading >>

Kinase-targeted Therapy in Subsets of Colorectal Cancer

September 22, 2023
“We have summarized some of our findings regarding the response of various subsets of CRC to kinase inhibitors […].” BUFFALO, NY- September 22, 2023 – A new editorial paper was published in Oncoscience (Volume 10) on June 27, 2023, entitled, “Kinase-targeted therapy in subsets of colorectal cancer.” In this new editorial, researchers Patricia M. Gomez Barila and Jan Paul Medema from the University of Amsterdam and Amsterdam University... continue reading >>

Exiting the Pandemic Together: Achieving Global Immunity and Equity

September 8, 2023
“While vaccination has been successful for the general population, it is crucial not to overlook the needs of immunocompromised individuals.” BUFFALO, NY- September 8, 2023 – A new editorial paper was published in Oncoscience (Volume 10) on September 1, 2023, entitled, “Exiting the pandemic together: achieving global immunity and equity.” In this new editorial, researchers Yuxin Ying, Jola Bytyci and Lennard YW Lee from Oxford Medical School... continue reading >>

Cancer Drug Development Yesterday, Today and Tomorrow

August 25, 2023
“One can expect that artificial intelligence (AI) will play some role in the future drug development.” BUFFALO, NY- August 25, 2023 – A new editorial paper was published in Oncoscience (Volume 10) on August 17, 2023, entitled, “Cancer drug development yesterday, today and tomorrow.” In this new editorial, researchers Elzbieta Izbicka and Robert T. Streeper from New Frontier Labs discuss the history of cancer drug development and how it has evolved... continue reading >>

Treatment Strategies for Adenoid Cystic Carcinoma of the Head and Neck

August 4, 2023
“Proton therapy […] seems to have decisive advantages with regard to the long-term survival of [adenoid cystic carcinoma] […]” BUFFALO, NY- August 4, 2023 – A new editorial paper was published in Oncoscience (Volume 10) on June 28, 2023, entitled, “Adenoid cystic carcinoma of the head and neck – treatment strategies of a highly malignant tumor with variable localizations.” In this new editorial, researchers Florian Dudde,... continue reading >>

Harnessing Machine Learning for Early Cancer Detection in Primary Care

July 21, 2023
“[Machine learning] has the potential to transform early cancer detection in primary care […]” — BUFFALO, NY- July 21, 2023 – A new editorial paper was published in Oncoscience (Volume 10) on June 9, 2023, entitled, “Transforming early cancer detection in primary care: harnessing the power of machine learning.” Cancer remains a significant global health burden, and early detection plays a crucial role in improving patient outcomes.... continue reading >>

Atypical Infections in Chronic Sinusitis: Thinking Outside the Box

July 14, 2023
“[…] in many cases [of chronic sinusitis] only symptom control is achieved.” — BUFFALO, NY- July 14, 2023 – A new research perspective was published in Oncoscience (Volume 10) on May 27, 2023, entitled, “Think outside the box – atypical infections in chronic sinusitis.” Inflammations of the paranasal sinuses represent a common clinical picture. The annual prevalence of chronic sinusitis in Europe is up to 10%. Sinusitis can be... continue reading >>

Cancer Cell Repopulation After Therapy: Which is the Mechanism?

June 23, 2023
“Approaches targeted to prevent this post-therapy cancer cell repopulation should be uncovered to prevent tumor relapse and thus increase overall survival from this devastating disease.” BUFFALO, NY- June 23, 2023 – A new research perspective was published in Oncoscience (Volume 10) on June 1, 2023, entitled, “Cancer cell repopulation after therapy: which is the mechanism?” The past two decades have brought great progress in the treatment of... continue reading >>

UPR-Induced Ovarian Cancer Cell Fusion: A Mechanism Favoring Drug Resistance?

May 26, 2023
“UPR [unfolded protein response] modulation in combination with conventional chemotherapeutic drug treatments of ovarian cancer patients could represent an interesting therapeutic strategy […]” Listen to an audio version of this press release BUFFALO, NY- May 26, 2023 – A new editorial paper was published in Oncoscience (Volume 10) on May 11, 2023, entitled, “UPR-induced ovarian cancer cell fusion: a mechanism favoring drug resistance?” In... continue reading >>

ATAD3A: A Molecular Determinant Favoring Head and Neck Cancer Development

April 28, 2023
“[…] developing targeted therapies that specifically inhibit ATAD3A in cancer cells while sparing normal cells will be a challenging but critical task.” Listen to an audio version of this press release BUFFALO, NY- April 28, 2023 – A new research perspective was published in Oncoscience (Volume 10) on April 4, 2023, entitled, “Mitochondrial regulator ATAD3A: a molecular determinant favoring head and neck cancer development.” In addition to... continue reading >>

New Method of Clustering Colorectal Cancer Patients Using DPE Sequencing

April 7, 2023
“[…] DPE analysis may have an important role in improving the diagnosis and management of CRC.” Listen to an audio version of this press release BUFFALO, NY- April 7, 2023 – A new editorial paper was published in Oncoscience (Volume 10) on March 23, 2023, entitled, “New method of clustering colorectal cancer patients using differential presence of exons (DPE) sequencing.” Colorectal cancer (CRC) is a heterogeneous disease that occurs in the... continue reading >>

Oncoscience | A Case for Routine Evaluation of HER2 Expression in Ductal Carcinoma In Situ

February 17, 2023
“We call upon the oncology community to embrace these results to avoid overtreatment of DCIS patients.” — Listen to an audio version of this press release BUFFALO, NY- February 17, 2023 – A new editorial paper was published in Oncoscience (Volume 10) on January 30, 2023, entitled, “HER2 expression should be routinely evaluated in DCIS to avoid under or overtreatment!” HER2 is more frequently overexpressed in ductal carcinoma in situ... continue reading >>

Oncoscience | A murine model for human early/immature T-cell precursor acute lymphoblastic leukemia (EITP ALL)

January 23, 2023
“As anticipated, we found that the onset of leukemia was significantly accelerated in Idh2R140Q/NHD13 double transgenic mice […]” — Listen to an audio version of this press release BUFFALO, NY- January 23, 2023 – A new research perspective was published in Oncoscience (Volume 9) on October 24, 2022, entitled, “A murine model for human early/immature T-cell precursor acute lymphoblastic leukemia (EITP ALL).” In this research... continue reading >>

Oncoscience | Association between tumor mutations and meningioma recurrence in Grade I/II disease

January 17, 2023
“Though meningioma patients often see favorable oncological outcomes, many tumors still recur post-surgically.” Listen to an audio version of this press release BUFFALO, NY- January 17, 2023 – A new research paper was published in Oncoscience (Volume 9) on December 9, 2022, entitled, “Association between tumor mutations and meningioma recurrence in Grade I/II disease.” Meningiomas are common intracranial tumors with variable prognoses not entirely... continue reading >>

Oncoscience | Rapamycin in the context of Pascal?s Wager: generative pre-trained transformer perspective

December 27, 2022
?The ability of the large language models, and other AI systems to make meaningful contributions to academic work may justify future co-authorship on academic perspective, review and research papers.? Listen to an audio version of this press release BUFFALO, NY- December 27, 2022 ? A new research perspective was published in Oncoscience (Volume 9) on December 21, 2022, entitled, ?Rapamycin in the context of Pascal?s Wager: generative pre-trained transformer perspective.? Large... continue reading >>