Oncoscience

Volume 8, 2021

Volume 8, 2021 is now on PubMed »

Volume 8 (2021)

About the Cover

The cover for Oncoscience Volume 8, 2021 features Figure 5, "Hypothetical scenarios of adding anti-aging treatments to current medical care," from https://doi.org/10.18632/oncoscience.547
by Mikhail V. Blagosklonny

Research Perspectives

Monitoring vascular normalization: new opportunities for mitochondrial inhibitors in breast cancer

https://doi.org/10.18632/oncoscience.523

Silvana  Mouron, Maria J. Bueno, Manuel  Muñoz, Miguel  Quintela-Fino

p 1-13

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Research Papers

The helix-loop-helix transcriptional regulator Id4 is required for terminal differentiation of luminal epithelial cells in the prostate

https://doi.org/10.18632/oncoscience.524

Dhanushka Hewa Bostanthirige, Shravan K. Komaragiri, Jugal B. Joshi, Majid  Alzahrani, Isha  Saini, Sanjay  Jain, Nathan J. Bowen, Matthew C. Havrda, Jaideep  Chaudhary

p 14-30

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Research Perspectives

Upper gastrointestinal cancers in Lynch syndrome: the time for surveillance is now

https://doi.org/10.18632/oncoscience.525

Shria  Kumar, Bryson W. Katona

p 31-33

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Research Perspectives

AKT as a therapeutic target for autophagy induction and cancer therapy

https://doi.org/10.18632/oncoscience.526

Qi  Wu, Yi  Tu, Guido  Kroemer, Oliver  Kepp

p 34-36

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Research Perspectives

Causation of increased prostate cancer in young men

https://doi.org/10.18632/oncoscience.527

Archie  Bleyer, Filippo  Spreafico, Ronald  Barr

p 37-39

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Research Perspectives

Balancing efficacy and quality of life measurements among metastatic renal cell carcinoma (RCC) studies

https://doi.org/10.18632/oncoscience.528

Jeanny B. Aragon-Ching

p 40-45

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Corrections

Correction: Lactate dehydrogenase A inhibition by small molecular entities: steps in the right direction

https://doi.org/10.18632/oncoscience.529

Btissame El Hassouni, Marika  Franczak, Mjriam  Capula, Christian M. Vonk, Valentina M. Gomez, Ryszard T. Smolenski, Carlotta  Granchi, Godefridus J. Peters, Filippo  Minutolo, Elisa  Giovannetti

p 46-46

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Research Perspectives

Importance of amino acids in brain parenchyma invasion by cancer cells

https://doi.org/10.18632/oncoscience.530

Alessio  Paone, Amani  Bouzidi, Serena  Rinaldo, Giorgio  Giardina, Francesca  Cutruzzolà

p 47-49

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Research Perspectives

Alternative splicing of CERS2 promotes cell proliferation and migration in luminal B subtype breast cancer cells

https://doi.org/10.18632/oncoscience.531

Trishna  Pani, Kajal  Rajput, Animesh  Kar, Ujjaini  Dasgupta

p 50-52

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Research Perspectives

A novel RNA- based approach to counteract EMT

https://doi.org/10.18632/oncoscience.532

Sabrina  Garbo, Marco  Tripodi, Cecilia  Battistelli

p 53-54

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Research Perspectives

A “two-hit” (chemo)therapy to improve checkpoint inhibition in cancer

https://doi.org/10.18632/oncoscience.533

Paolo  Falvo, Stefania  Orecchioni, Alessro  Raveane, Giulia  Mitola, Francesco  Bertolini

p 55-57

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Research Perspectives

p53 activation vs. stabilization: an acetylation tale from the C-terminal tail

https://doi.org/10.18632/oncoscience.534

Ning  Kon, Wei  Gu

p 58-60

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Research Papers

Constitutive activation of MEK5 promotes a mesenchymal and migratory cell phenotype in triple negative breast cancer

https://doi.org/10.18632/oncoscience.535

Margarite D. Matossian, Van T. Hoang, Hope E. Burks, Jacqueline  La, Steven  Elliott, Courtney  Brock, Douglas B. Rusch, Aaron  Buechlein, Kenneth P. Nephew, Akshita  Bhatt, Jane E. Cavanaugh, Patrick T. Flaherty, Bridgette M. Collins-Burow, Matthew E. Burow

p 61-71

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Research Perspectives

Radiomic-based diagnostics in oncology: challenges toward clinical practice

https://doi.org/10.18632/oncoscience.536

Emanuele  Barabino, Giovanni  Rossi, Alessandro  Fedeli, Giuseppe  Cittadini, Carlo  Genova

p 72-73

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Research Perspectives

SCIRT lncRNA slows the formation of tumour initiating cells in breast cancer

https://doi.org/10.18632/oncoscience.537

Alex de Giorgio, Lero  Castellano

p 74-75

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Research Perspectives

A precision approach to breast cancer treatment based on cell lineage-specific vulnerabilities

https://doi.org/10.18632/oncoscience.538

Jay S. Desgrosellier

p 76-79

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Research Perspectives

Re-enforcing the strategy of targeting MEK/ERK signaling to overcome acquired resistance to third generation EGFR inhibitors

https://doi.org/10.18632/oncoscience.539

Wen  Zhao, Shi-Yong  Sun

p 80-81

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Research Perspectives

Advances in culture methods for acute myeloid leukemia research

https://doi.org/10.18632/oncoscience.540

Krishnapriya  Syama, Eman M.  Hassan, Shan  Zou

p 82-90

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Research Perspectives

Determining the utility of a screening program to reduce the incidence of HPV driven oropharyngeal cancer

https://doi.org/10.18632/oncoscience.541

Sarju  Vasani, Ian  Frazer, Chamindie  Punyadeera

p 91-93

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Research Perspectives

New insight into the role of MDMX in MDM2-mediated p53 degradation and anti-cancer drug development

https://doi.org/10.18632/oncoscience.542

Jing  Yang, Yanping  Zhang

p 94-96

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Research Perspectives

Tune the channel: TRPM8 targeting in prostate cancer

https://doi.org/10.18632/oncoscience.543

Alessandro  Alaimo, Dario  De Felice, Sacha  Genovesi, Marco  Lorenzoni, Andrea  Lunardi

p 97-100

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Editorials

Taking action early to manage emergence of acquired resistance to osimertinib or other third generation EGFR inhibitors

https://doi.org/10.18632/oncoscience.544

Guangzhi  Ma, Shi-Yong  Sun

p 101-102

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Editorial Perspective

The hyperfunction theory of aging: three common misconceptions

https://doi.org/10.18632/oncoscience.545

Mikhail V.  Blagosklonny

p 103-107

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Corrections

Correction: Targeting focal adhesion kinase overcomes erlotinib resistance in smoke induced lung cancer by altering phosphorylation of epidermal growth factor receptor

https://doi.org/10.18632/oncoscience.546

Hitendra S.  Solanki, Remya  Raja, Alex  Zhavoronkov, Ivan V.  Ozerov, Artem V.  Artemov, Jayshree  Advani, Aneesha  Radhakrishnan, Niraj  Babu, Vinuth N.  Puttamallesh, Nazia  Syed, Vishalakshi  Nanjappa, Tejaswini  Subbannayya, Nandini A.  Sahasrabuddhe, Arun H.  Patil, T.S. Keshava  Prasad, Daria  Gaykalova, Xiaofei  Chang, Rachana  Sathyendran, Premendu  Prakash Mathur, Annapoorni  Rangarajan, David  Sidransky, Akhilesh  Pandey, Evgeny  Izumchenko, Harsha  Gowda, Aditi  Chatterjee

p 108-109

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Research Perspectives

No limit to maximal lifespan in humans: how to beat a 122-year-old record

https://doi.org/10.18632/oncoscience.547

Mikhail V.  Blagosklonny

p 110-119

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Clinical Reports

Berry anthocyanidins inhibit intestinal polyps and colon tumors by modulation of Src, EGFR and the colon inflammatory environment

https://doi.org/10.18632/oncoscience.548

Ashley M.  Mudd, Tao  Gu, Radha  Munagala, Jeyaprakash  Jeyabalan, Mostafa  Fraig, Nejat K.  Egilmez, Ramesh C.  Gupta

p 120-133

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Clinical Reports

VTT-006, an anti-mitotic compound, binds to the Ndc80 complex and suppresses cancer cell growth in vitro

https://doi.org/10.18632/oncoscience.549

Leena J.  Laine, Jenni H.E.  Mäki-Jouppila, Emma  Kutvonen, Pekka  Tiikkainen, Thomas K.M.  Nyholm, Jerry F.  Tien, Neil T.  Umbreit, Ville  Härmä, Lila  Kallio, Trisha N.  Davis, Charles L.  Asbury, Antti  Poso, Gary J.  Gorbsky, Marko J.  Kallio

p 134-153

Abstract |  PDF |  Full Text |  Supplementary Material  |  Supplementary Movie 1 |  Supplementary Movie 2 |  Supplementary Movie 3 |  Supplementary Movie 4 |  Supplementary Movie 5 |  How to Cite